PLASMA Lp(a) AND t-PA-PAI-1 COMPLEX LEVELS IN CORONARY HEART DISEASE

In this study we investigated serum Lp(a) and plasma t-PA-PAI-1 complex levels in patients with coronary heart disease (CHD). Serum total cholesterol, triglyceride, LDL and VDL cholesterol levels (p < 0.001) and HDL cholesterol levels (p < 0.01) in patients group were found to be significantly...

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Bibliographic Details
Published in:Thrombosis research 1996-07, Vol.83 (1), p.77-85
Main Authors: Süer, Selma, Ulutin, Turgut, Sönmez, Hüseyin, Kökoǧlu, Emine, Üçişik, Nergiz, Bayram, Çiǧdem, Sultuybek, Gönül
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Arteriosclerosis - blood
Arteriosclerosis - etiology
Biological and medical sciences
Cardiology. Vascular system
Case-Control Studies
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Cholesterol, VLDL - blood
Coronary Disease - blood
Coronary Disease - etiology
Coronary heart disease
Female
Heart
Humans
Lipoprotein(a) - blood
Lp(a)
Male
Medical sciences
Middle Aged
Plasminogen Activator Inhibitor 1 - blood
t-PA-PAI-1 complex
Tissue Plasminogen Activator - blood
Triglycerides - blood
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Summary:In this study we investigated serum Lp(a) and plasma t-PA-PAI-1 complex levels in patients with coronary heart disease (CHD). Serum total cholesterol, triglyceride, LDL and VDL cholesterol levels (p < 0.001) and HDL cholesterol levels (p < 0.01) in patients group were found to be significantly different from those in control group. The mean Lp(a) and t-PA-PAI-1 complex levels in patients with coronary heart disease were significantly higher as compared to control group (p < 0.001). This data indicate that the elevated levels of serum Lp(a) and plasma t-PA-PAI-1 complex may play an important role in the pathogenesis of coronary atherosclerosis.
ISSN:0049-3848
1879-2472
DOI:10.1016/0049-3848(96)00105-3