Individual hormone replacement therapy

Although hormone replacement therapy is widely used in western countries, compliance is not very good; only a minor proportion of women starting the treatment continue it for over 5 years. However, long-term treatment is essential for primary prevention of cardiovascular diseases and osteoporosis. O...

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Bibliographic Details
Published in:Maturitas 1996-05, Vol.23, p.S87-S90
Main Authors: Tuimala, Risto J., Vihtamäki, Tarja
Format: Article
Language:English
Subjects:
Administration, Cutaneous
Administration, Oral
Biological and medical sciences
Climacteric - drug effects
Cost-Benefit Analysis
Dose-Response Relationship, Drug
Estrogen Replacement Therapy - economics
Estrogen Replacement Therapy - methods
Estrogen replacement treatment (ERT)
Estrogens - blood
Female
Hormone replacement therapy (HRT)
Hormones. Endocrine system
Humans
Individual
Long-Term Care
Medical sciences
Pharmacology. Drug treatments
Progestins - administration & dosage
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Description
Summary:Although hormone replacement therapy is widely used in western countries, compliance is not very good; only a minor proportion of women starting the treatment continue it for over 5 years. However, long-term treatment is essential for primary prevention of cardiovascular diseases and osteoporosis. One reason for low compliance is that treatment is not planned individually. After using a fixed estradiol dose, serum levels of estradiol show 10-fold differences between subjects, independently of the routes of administration. This article briefly summarizes the possibility of using tailored treatment and thus improving long-term compliance with HRT.
ISSN:0378-5122
1873-4111
DOI:10.1016/0378-5122(96)01019-5