Cardioprotective effects of ovarian hormones

This paper reviews the evidence regarding the cardioprotective effects of oestrogen replacement therapy in postmenopausal women. Oestrogens have been shown to improve serum lipid profiles, carbohydrate metabolism, and insulin sensitivity; prevent the formation and development of atherosclerotic plaq...

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Bibliographic Details
Published in:European heart journal 1996-08, Vol.17 (suppl-D), p.15-19
Main Authors: Rosano, G. M. C., Chierchia, S. L., Leonardo, F., Beale, C. M., Collins, P.
Format: Article
Language:English
Subjects:
Animals
Atherosclerosis
Blood Pressure
Carbohydrates - blood
coronary artery disease
Coronary Disease - blood
Coronary Disease - physiopathology
Coronary Disease - prevention & control
Estrogen Replacement Therapy
Female
Humans
ischaemia
Lipids - blood
oestrogen replacement therapy
postmenopausal women
Postmenopause - drug effects
Postmenopause - metabolism
Risk Factors
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Summary:This paper reviews the evidence regarding the cardioprotective effects of oestrogen replacement therapy in postmenopausal women. Oestrogens have been shown to improve serum lipid profiles, carbohydrate metabolism, and insulin sensitivity; prevent the formation and development of atherosclerotic plaque; reduce blood pressure and plasma fibrinogen levels; and favourably affect overall cardiac function. Thus, oestrogen replacement therapy may prevent or inhibit the progression of existing coronary disease, and may also have a protective effect against acute cardiovascular and cerebrovascular ischaemic events.
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/17.suppl_D.15