MRI of the spine in cobalamin deficiency : the value of examining both spinal cord and bone marrow

We observed a case of pernicious anaemia in which MRI of the spine demonstrated both intrinsic lesions of the spinal cord and abnormal signal in the bone marrow. The latter resolved with replacement therapy. Only partial recovery of the cord lesions was observed.

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Bibliographic Details
Published in:Neuroradiology 1996-08, Vol.38 (6), p.511-515
Main Authors: DUPREZ, T. P, GILLE, M, VANDE BERG, B. C, MALGHEM, J, GRANDIN, C. B, MICHEL, P, GHARIANI, S, MALDAGUE, B. E
Format: Article
Language:English
Subjects:
Aged
Anemia, Pernicious - diagnosis
Anemia, Pernicious - drug therapy
Anemias. Hemoglobinopathies
Biological and medical sciences
Biopsy, Needle
Bone Marrow - pathology
Bone Marrow Diseases - diagnosis
Bone Marrow Diseases - drug therapy
Diseases of red blood cells
Female
Hematologic and hematopoietic diseases
Humans
Injections, Intramuscular
Magnetic Resonance Imaging
Medical sciences
Spinal Cord - pathology
Spinal Cord Diseases - diagnosis
Spinal Cord Diseases - drug therapy
Vitamin B 12 - administration & dosage
Vitamin B 12 Deficiency - diagnosis
Vitamin B 12 Deficiency - drug therapy
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Description
Summary:We observed a case of pernicious anaemia in which MRI of the spine demonstrated both intrinsic lesions of the spinal cord and abnormal signal in the bone marrow. The latter resolved with replacement therapy. Only partial recovery of the cord lesions was observed.
ISSN:0028-3940
1432-1920
DOI:10.1007/BF00626083