Prominent Osseous and Unusual Dermatologic Manifestations of Early Syphilis in Two Patients with Discordant Serological Statuses for Human Immunodeficiency Virus Infection

Numerous case reports of atypical and/or severe forms of syphilis in individuals coinfected with human immunodeficiency virus (HIV) have led many authorities to conclude that HIV exacerbates early syphilitic infection. Herein we report prominent osseous and unusual dermatologic manifestations of ear...

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Bibliographic Details
Published in:Clinical infectious diseases 1996-09, Vol.23 (3), p.462-467
Main Authors: Rademacher, Steven E., Radolf, Justin D.
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Bacterial diseases
Biological and medical sciences
Bones
Clinical Articles
Female
HIV
HIV infections
HIV Seronegativity
HIV Seropositivity - complications
Human bacterial diseases
human immunodeficiency virus
Humans
Infections
Infectious diseases
Lesions
Medical sciences
Miscellaneous
Neurosyphilis
Osteitis - diagnosis
Osteitis - microbiology
Penicillin
Syphilis
Syphilis - diagnosis
Syphilis - physiopathology
Syphilis - virology
Syphilis, Cutaneous - physiopathology
Syphilis, Cutaneous - virology
Tibia
Treponema pallidum
Wasserman test
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Summary:Numerous case reports of atypical and/or severe forms of syphilis in individuals coinfected with human immunodeficiency virus (HIV) have led many authorities to conclude that HIV exacerbates early syphilitic infection. Herein we report prominent osseous and unusual dermatologic manifestations of early syphilis in two individuals whose serostatuses for HIV infection were discordant. Our cases emphasize the need for caution before conclusions are drawn from anecdotal data about the interactions between HIV infection and syphilis.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/23.3.462