Increases in depression after cholesterol-lowering drug treatment

To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a l...

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Bibliographic Details
Published in:Behavioral medicine (Washington, D.C.) D.C.), 1996, Vol.22 (2), p.82-84
Main Authors: Davidson, K W, Reddy, S, McGrath, P, Zitner, D, MacKeen, W
Format: Article
Language:English
Subjects:
Anticholesteremic Agents - adverse effects
Anticholesteremic Agents - therapeutic use
Blood
Case studies
Cholesterol
Cholesterol - blood
Depression
Depression - blood
Depression - chemically induced
Depression - psychology
Drugs
Factors
Humans
Hypercholesterolemia - blood
Hypercholesterolemia - drug therapy
Hypercholesterolemia - psychology
Male
Middle Aged
Personality Inventory
Risk Factors
Treatment
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Summary:To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a lipid clinic. All of the patients' cholesterol levels were reduced after the 6-week intervention, and 4 of the patients' depression scores increased; scores of 2 of the 4 met the criteria for mild clinical depression. Further study of possible links among low cholesterol, depressive symptoms, and serotonergic activity is needed.
ISSN:0896-4289
1940-4026
DOI:10.1080/08964289.1996.9933768