Value of fetal fibronectin as a predictor of preterm delivery for a low-risk population

OBJECTIVE: We examined clinical value of cervical fetal fibronectin detection by a quantitative enzyme-linked immunosorbent assay as a predictor of preterm delivery in a population (n = 111) of middle-class pregnant women considered to be at low risk for preterm delivery. STUDY DESIGN: In this prosp...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 1996-10, Vol.175 (4), p.1054-1056
Main Authors: Greenhagen, Julia B., Van Wagonera, Jennifer, Dudley, Donald, Hunter, Cheri, Mitchell, Murray, Logsdon, Valerie, Casal, David, Varner, Michael
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Enzyme-Linked Immunosorbent Assay
Evaluation Studies as Topic
Female
Fetal Blood
Fetal fibronectin
Fibronectins - blood
Gynecology. Andrology. Obstetrics
Humans
Management. Prenatal diagnosis
Medical sciences
Obstetric Labor, Premature
population screening
Predictive Value of Tests
Pregnancy
Pregnancy. Fetus. Placenta
preterm birth
Prospective Studies
Risk Factors
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Summary:OBJECTIVE: We examined clinical value of cervical fetal fibronectin detection by a quantitative enzyme-linked immunosorbent assay as a predictor of preterm delivery in a population (n = 111) of middle-class pregnant women considered to be at low risk for preterm delivery. STUDY DESIGN: In this prospective study, fetal fibronectin samples from cervicovaginal secretions were obtained biweekly from 24 to 34 weeks' gestation. RESULTS: Twenty-two (20%) patients had at least one positive fetal fibronectin test result. Eleven women (10%) were delivered spontaneously at
ISSN:0002-9378
1097-6868
DOI:10.1016/S0002-9378(96)80052-4