Molecular characterization of HLA-A6803

More than 200 HLA class I and class II typing laboratories participate in the International Cell Exchange (ICE). Laboratories participating in the typing of HLA class I molecules as part of the exchange are sent four unknown samples each month upon which class I typing is completed. The participatin...

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Bibliographic Details
Published in:Immunogenetics (New York) 1996, Vol.45 (1), p.78-79
Main Authors: Ellexson, M, Lau, M, Terasaki, P, Hildebrand, W
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Base Sequence
Cloning, Molecular
HLA-A Antigens - genetics
Humans
Molecular Sequence Data
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Summary:More than 200 HLA class I and class II typing laboratories participate in the International Cell Exchange (ICE). Laboratories participating in the typing of HLA class I molecules as part of the exchange are sent four unknown samples each month upon which class I typing is completed. The participating laboratories then communicate the class I type identified, the data from all participants is combined, and a report assessing class I typing consistency from laboratory to laboratory is published. Laboratories participating in the ICE have historically determined a class I type using alloantibodies: however, the realization that serologic typing cannot discriminate among all class I subtypes has led to the implementation of molecular class I HLA typing methods (DBO).
ISSN:0093-7711
DOI:10.1007/s002510050172