A Population-Based Serologic Survey of Helicobacter pylori Infection in Children and Adolescents in the United States

To provide more accurate estimates of Helicobacter pylori infection in the US population, IgG antibody levels were measured in serum from 2581 persons aged 6–19 years examined during phase 1 of the third National Health and Nutrition Examination Survey. Overall, 24.8% of participants had evidence of...

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Bibliographic Details
Published in:The Journal of infectious diseases 1996-11, Vol.174 (5), p.1120-1123
Main Authors: Staat, Mary A., Kruszon-Moran, Deanna, McQuillan, Geraldine M., Kaslow, Richard A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Antibodies, Bacterial - blood
Bacterial diseases
Bacterial diseases of the digestive system and abdomen
Biological and medical sciences
Child
Children
Concise Communications
Ethnic groups
Female
Health surveys
Helicobacter Infections - epidemiology
Helicobacter Infections - ethnology
Helicobacter pylori
Helicobacter pylori - immunology
Hispanic Americans
Human bacterial diseases
Humans
Infections
Infectious diseases
Male
Medical sciences
Mexican American education
Population estimates
Poverty
Predisposing factors
Socioeconomic Factors
United States - epidemiology
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Summary:To provide more accurate estimates of Helicobacter pylori infection in the US population, IgG antibody levels were measured in serum from 2581 persons aged 6–19 years examined during phase 1 of the third National Health and Nutrition Examination Survey. Overall, 24.8% of participants had evidence of H. pylori infection. Infection was strongly associated with increasing age (X 2trend, P < .01) and being nonwhite (17.0% of non-Hispanic whites vs. 40.1% of non-Hispanic blacks and 42.0% of Mexican Americans infected). In a multivariate logistic regression model, H. pylori infection was significantly associated with increasing age (odds ratio [OR] = 1.07/year), being nonwhite (non-Hispanic black OR = 2.6 or Mexican American OR = 1.8), poverty (OR = 1.5), crowding (OR = 5.6), and- head of household education level (OR = 1.8). In Mexican Americans, infection was associated with birth outside the United States or Canada in the univariate analyses but was not significantly associated after adjustment for age, poverty, crowding, and head of household education level.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/174.5.1120