Enlarged similarity of nucleic acid sequences

The concept of nucleic acid sequence base alternations is presented. The number of base alterations for the sequences of different length is established. The definition of "enlarged similarity" of nucleic acids sequences on the basis of sequence base alterations is introduced. Mutual infor...

Full description

Saved in:
Bibliographic Details
Published in:DNA research 1996-06, Vol.3 (3), p.157-164
Main Authors: Korotkov, E V, Korotkova, M A
Format: Article
Language:English
Subjects:
Base Sequence
Entropy
Models, Genetic
Molecular Sequence Data
Sequence Homology, Nucleic Acid
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The concept of nucleic acid sequence base alternations is presented. The number of base alterations for the sequences of different length is established. The definition of "enlarged similarity" of nucleic acids sequences on the basis of sequence base alterations is introduced. Mutual information between sequences is used as a quantitative measure of enlarged similarity for two compared sequences. The method of mutual information calculation is developed considering the correlation of bases in compared sequences. The definitions of correlated similarity and evolution similarity between compared sequences are given. Results of the use of enlarged similarity approach for DNA sequences analysis are discussed.
ISSN:1340-2838
1756-1663
DOI:10.1093/dnares/3.3.157