Multicentric reticulohistiocytosis

We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis;...

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Bibliographic Details
Published in:Clinical rheumatology 1996-01, Vol.15 (1), p.62-66
Main Authors: Kocanaogullari, H, Ozsan, H, Oksel, F, Ozturk, G, Kandiloglu, G, Ustun, E E, Doganavsargil, E
Format: Article
Language:English
Subjects:
Adult
Antirheumatic Agents - administration & dosage
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - diagnosis
Arthritis, Rheumatoid - physiopathology
Azathioprine - administration & dosage
Azathioprine - therapeutic use
Biopsy, Needle
Diagnosis, Differential
Histiocytosis - diagnosis
Histiocytosis - drug therapy
Histiocytosis - pathology
Histiocytosis - physiopathology
Humans
Male
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Summary:We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis; however, biopsies from the nodules on the oral mucosa and ear revealed multicentric reticulohistiocytosis. The large nodule over the olecranon process, simulating a rheumatoid nodule but diagnosed as multicentric reticulohistiocytosis with biopsy; ulcerated and haemorrhagic nodules on the oral mucosa; and rapidly progressive joint destructions make our case interesting.
ISSN:0770-3198
1434-9949
DOI:10.1007/BF02231688