Functional characterization of brain tumors: An overview of the potential clinical value

Early detection and characterization are still challenging issues in the diagnostic approach to brain tumors. Among functional imaging techniques, a clinical role for positron emission tomography studies with [ 18F]-fluorodeoxyglucose and for single photon emission computed tomography studies with [...

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Bibliographic Details
Published in:Nuclear medicine and biology 1996-08, Vol.23 (6), p.699-715
Main Authors: Brunetti, Arturo, Alfano, Bruno, Soricelli, Andrea, Tedeschi, Enrico, Mainolfi, Ciro, Covelli, Eugenio M., Aloj, Luigi, Panico, Maria Rosaria, Bazzicalupo, Lucio, Salvatore, Marco
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain Neoplasms - diagnosis
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - pathology
Brain tumors
Emission computed tomography
Functional imaging
Functional MRI
Humans
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Medical sciences
Neurology
Tomography, Emission-Computed
Tomography, Emission-Computed, Single-Photon
Tumors of the nervous system. Phacomatoses
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Summary:Early detection and characterization are still challenging issues in the diagnostic approach to brain tumors. Among functional imaging techniques, a clinical role for positron emission tomography studies with [ 18F]-fluorodeoxyglucose and for single photon emission computed tomography studies with [ 201T1]-thallium-chloride has emerged. The clinical role of magnetic resonance spectroscopy is still being defined, whereas functional magnetic resonance imaging seems able to provide useful data for presurgical localization of critical cortical areas. Integration of morphostructural information provided by computed tomography and magnetic resonance imaging, with functional characterization and cyto-histologic evaluation of biologic markers, may assist in answering the open diagnostic questions concerning brain tumors.
ISSN:0969-8051
1872-9614
DOI:10.1016/0969-8051(96)00069-8