Transvalvular Impedance (TVI) Recording Under Electrical and Pharmocological Cardiac Stimulation

The cardiac electric impedance was recorded between right atrium and ventricle, throughout the cardiac cycle, by means of a tripolar single pass lead for VDD pacing. The transvalvular impedance signal (TVI) is a sharp periodic wave, with high signal‐to‐noise ratio, that is detected exclusively in th...

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Bibliographic Details
Published in:Pacing and clinical electrophysiology 1996-11, Vol.19 (11), p.1689-1693
Main Authors: DI GREGORIO, F., MORRA, A., FINESSO, M., BONGIORNI, M.G.
Format: Article
Language:English
Subjects:
Adrenergic Agonists - pharmacology
Algorithms
Animals
Atrial Function, Right - drug effects
Blood Pressure - drug effects
cardiac impedance
Cardiac Pacing, Artificial - methods
Cardiotonic Agents - pharmacology
Electric Impedance
Electric Stimulation
Electrocardiography
Epinephrine - pharmacology
Equipment Design
Equipment Safety
fibrillation detection
Heart - drug effects
Heart - physiology
Heart Rate - drug effects
Ouabain - pharmacology
Pacemaker, Artificial
rate responsive pacing
Reproducibility of Results
Signal Processing, Computer-Assisted
Swine
Swine, Miniature
Systole
Ventricular Fibrillation - diagnosis
Ventricular Function, Right - drug effects
Ventricular Pressure - drug effects
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Summary:The cardiac electric impedance was recorded between right atrium and ventricle, throughout the cardiac cycle, by means of a tripolar single pass lead for VDD pacing. The transvalvular impedance signal (TVI) is a sharp periodic wave, with high signal‐to‐noise ratio, that is detected exclusively in the presence of cardiac mechanical activity. The minimum TVI value is attained during the atrial systole, the maximum at the end of ventricular systole. Different parameters of TVI waveform are affected by changes in the inotropic state, and could therefore be proposed as potential signals for new rate responsive algorithms based on the correlation between inotropic and chronotropic regulation. The signal might be used, moreover, for pacing and sensing validation in autoregulating pacemakers and for fibrillation recognition in ICDs.
ISSN:0147-8389
1540-8159
DOI:10.1111/j.1540-8159.1996.tb03207.x