ST Reelevation at Reperfusion is Associated with the Occurrence of Late Potentials in Patients with Acute Anterior Infarction

• Published in: Pacing and clinical electrophysiology 1996-11, Vol.19 (11), p.1914-1917
• Main Authors: OCHIAI, MASAHIKO, ISSHIKI, TAKAAKI, OSHIMA, AKIO, TOYOIZUMI, HIDEKI, KONDO, KIYOYUKI, TAKESHITA, SATOSHI, SATO, TOMOHIDE, MIYASHITA, HIDEO
• Format: Article
• Language: English
• Subjects: Action Potentials - physiology; acute myocardial infarction; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Cardiac Volume; Cineradiography; Coronary Angiography; Coronary Disease - diagnostic imaging; Coronary Disease - physiopathology; Coronary Disease - therapy; Electrocardiography; Female; Follow-Up Studies; Humans; late potentials; Male; Middle Aged; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - physiopathology; Myocardial Infarction - therapy; primary angioplasty; Signal Processing, Computer-Assisted; ST reelevation; Stroke Volume; Treatment Outcome; Vascular Patency; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left
• ISSN: 0147-8389; 1540-8159
• DOI: 10.1111/j.1540-8159.1996.tb03252.x

The relationship between ST reelevation at reperfusion and the occurrence of late potentials (LPS) in 35 patients with a first anterior infarction who had single vessel disease was investigated. All patients underwent a successful primary angioplastv and had a patent infarct related artery confirmed angiographically 4 weeks later. Patients were classified into groups based on changes in the ST level at reperfusion: patients with ST reelevation (group A, n = 22) and patients without ST reelevation (group B, n = 13). Signal‐averaged ECG was performed 4 weeks after primary angioplasty to detect LPS. Cineventriculography was performed to measure left ventricular ejection fraction (LVEF) and evaluate regional wall motion of the infarct area (SD/chords). LPS were present in eight of the 22 group A patients (36%) and in none of the 13 group B patients (P < 0.05). Left ventricular function was impaired in patients in group A compared with patients in group B (LVEF: 51 ± 12 vs 63 ± 10, P < 0.01; SD/chords: −2.7 ± 0.9 vs −1.9 ± 1.1, P < 0.05). These data suggest that ST reelevation and myocardial damage at reperfusion are associated with the occurrence of LPS in patients with successfully recanalized infarct related arteries after acute anterior infarction.