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Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease
We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph no...
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Published in: | European journal of pediatrics 1996-12, Vol.155 (12), p.1015-1017 |
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container_end_page | 1017 |
container_issue | 12 |
container_start_page | 1015 |
container_title | European journal of pediatrics |
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creator | DE HEER-GROEN, T. A PRAKKEN, A. B. J BAX, N. M. A VAN DIJKEN, P. J |
description | We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely.
Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia. |
doi_str_mv | 10.1007/BF02532521 |
format | article |
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Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.</description><identifier>ISSN: 0340-6199</identifier><identifier>EISSN: 1432-1076</identifier><identifier>DOI: 10.1007/BF02532521</identifier><identifier>PMID: 8956935</identifier><identifier>CODEN: EJPEDT</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Adolescent ; Anemia - drug therapy ; Anemia - etiology ; Anemias. Hemoglobinopathies ; Biological and medical sciences ; Castleman Disease - diagnosis ; Castleman Disease - physiopathology ; Castleman Disease - surgery ; Diseases of red blood cells ; Female ; Hematologic and hematopoietic diseases ; Humans ; Iron - therapeutic use ; Medical sciences</subject><ispartof>European journal of pediatrics, 1996-12, Vol.155 (12), p.1015-1017</ispartof><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c243t-4d533be6401dfb17d884300f5d86731e83d4014f06b46df778de3bed40a4c60a3</citedby><cites>FETCH-LOGICAL-c243t-4d533be6401dfb17d884300f5d86731e83d4014f06b46df778de3bed40a4c60a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2502991$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8956935$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DE HEER-GROEN, T. A</creatorcontrib><creatorcontrib>PRAKKEN, A. B. J</creatorcontrib><creatorcontrib>BAX, N. M. A</creatorcontrib><creatorcontrib>VAN DIJKEN, P. J</creatorcontrib><title>Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease</title><title>European journal of pediatrics</title><addtitle>Eur J Pediatr</addtitle><description>We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely.
Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.</description><subject>Adolescent</subject><subject>Anemia - drug therapy</subject><subject>Anemia - etiology</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Biological and medical sciences</subject><subject>Castleman Disease - diagnosis</subject><subject>Castleman Disease - physiopathology</subject><subject>Castleman Disease - surgery</subject><subject>Diseases of red blood cells</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Iron - therapeutic use</subject><subject>Medical sciences</subject><issn>0340-6199</issn><issn>1432-1076</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><recordid>eNpF0E1LAzEQBuAgSq3Vi3chB_EgrCabbDZ71GK1UPCiXpfZzayN7EdNUmT_vZGWehqY92FgXkIuObvjjOX3jwuWZiLNUn5EplyKNOEsV8dkyoRkieJFcUrOvP9iERdcT8hEF5kqRDYlH0s39DSs0cFmpA699QH6QDtbu6Eeg60p9ICdBWp7CpSLZERwydAa-mldS39sWNM5-NBiBz011iN4PCcnDbQeL_ZzRt4XT2_zl2T1-rycP6ySOpUiJNJkQlSoJOOmqXhutJaCsSYzWuWCoxYmRrJhqpLKNHmuDUYflyBrxUDMyM3u7sYN31v0oeysr7Ftocdh68tcKy4k1xHe7mB8y3uHTblxtgM3lpyVfyWW_yVGfLW_uq06NAe6by3m1_scfA1t46CvrT-wNGNpUXDxCxEld9E</recordid><startdate>19961201</startdate><enddate>19961201</enddate><creator>DE HEER-GROEN, T. A</creator><creator>PRAKKEN, A. B. J</creator><creator>BAX, N. M. A</creator><creator>VAN DIJKEN, P. J</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19961201</creationdate><title>Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease</title><author>DE HEER-GROEN, T. A ; PRAKKEN, A. B. J ; BAX, N. M. A ; VAN DIJKEN, P. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c243t-4d533be6401dfb17d884300f5d86731e83d4014f06b46df778de3bed40a4c60a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adolescent</topic><topic>Anemia - drug therapy</topic><topic>Anemia - etiology</topic><topic>Anemias. Hemoglobinopathies</topic><topic>Biological and medical sciences</topic><topic>Castleman Disease - diagnosis</topic><topic>Castleman Disease - physiopathology</topic><topic>Castleman Disease - surgery</topic><topic>Diseases of red blood cells</topic><topic>Female</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Iron - therapeutic use</topic><topic>Medical sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DE HEER-GROEN, T. A</creatorcontrib><creatorcontrib>PRAKKEN, A. B. J</creatorcontrib><creatorcontrib>BAX, N. M. A</creatorcontrib><creatorcontrib>VAN DIJKEN, P. J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DE HEER-GROEN, T. A</au><au>PRAKKEN, A. B. J</au><au>BAX, N. M. A</au><au>VAN DIJKEN, P. J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease</atitle><jtitle>European journal of pediatrics</jtitle><addtitle>Eur J Pediatr</addtitle><date>1996-12-01</date><risdate>1996</risdate><volume>155</volume><issue>12</issue><spage>1015</spage><epage>1017</epage><pages>1015-1017</pages><issn>0340-6199</issn><eissn>1432-1076</eissn><coden>EJPEDT</coden><abstract>We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely.
Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>8956935</pmid><doi>10.1007/BF02532521</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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language | eng |
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subjects | Adolescent Anemia - drug therapy Anemia - etiology Anemias. Hemoglobinopathies Biological and medical sciences Castleman Disease - diagnosis Castleman Disease - physiopathology Castleman Disease - surgery Diseases of red blood cells Female Hematologic and hematopoietic diseases Humans Iron - therapeutic use Medical sciences |
title | Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease |
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