Electrophysiological properties of rat subicular neurons in vitro

The electrophysiological properties of 46 bursting cells and 39 regular firing cells were studied in the subiculum of rat combined hippocampal-entorhinal cortex slices. In bursting cells we found a significantly higher resting membrane potential than in regular firing cells. Upon hyperpolarization b...

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Bibliographic Details
Published in:Neuroscience letters 1996-12, Vol.220 (1), p.41-44
Main Authors: Behr, J., Empson, R.M., Schmitz, D., Gloveli, T., Heinemann, U.
Format: Article
Language:English
Subjects:
Accommodation
Afterhyperpolarization
Animals
Biological and medical sciences
Bursting cells
Central nervous system
Electrophysiology
Fundamental and applied biological sciences. Psychology
Hippocampus - physiology
Intracellular recording
Membrane Potentials - physiology
Neurons - physiology
Rats
Rats, Wistar
Regular firing cells
Subiculum
Vertebrates: nervous system and sense organs
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Summary:The electrophysiological properties of 46 bursting cells and 39 regular firing cells were studied in the subiculum of rat combined hippocampal-entorhinal cortex slices. In bursting cells we found a significantly higher resting membrane potential than in regular firing cells. Upon hyperpolarization both cell types expressed a delayed inward rectification with a subsequent afterdepolarization. While in regular firing cells longer tasting depolarizing current injection caused a train of action potentials with a rather marked decline of discharge frequency, bursting cells displayed only little frequency accommodation. Regular firing cells usually displayed a fast and a slow afterhyperpolarization following a train of action potentials, while bursting neurons present only a slow afterhyperpolarization.
ISSN:0304-3940
1872-7972
DOI:10.1016/S0304-3940(96)13242-0