Progress towards an alanine/ESR therapy level reference dosimetry service at NPL

This paper describes work being carried out at the National Physical Laboratory towards the establishment of an alanine reference dosimetry service for radiotherapy applications. A precision fused quartz holder has been constructed to allow precise positioning of alanine dosimeters in the ESR cavity...

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Bibliographic Details
Published in:Applied radiation and isotopes 1996-11, Vol.47 (11), p.1171-1175
Main Authors: Sharpe, P.H.G., Rajendran, K., Sephton, J.P.
Format: Article
Language:English
Subjects:
Alanine - chemistry
Alanine - radiation effects
Electron Spin Resonance Spectroscopy - instrumentation
Electron Spin Resonance Spectroscopy - methods
Electron Spin Resonance Spectroscopy - standards
Free Radicals - analysis
Free Radicals - radiation effects
Gamma Rays
Humans
Photons
Radiometry - instrumentation
Radiometry - methods
Radiometry - standards
Radiotherapy Dosage
Radiotherapy, High-Energy
Reference Standards
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Summary:This paper describes work being carried out at the National Physical Laboratory towards the establishment of an alanine reference dosimetry service for radiotherapy applications. A precision fused quartz holder has been constructed to allow precise positioning of alanine dosimeters in the ESR cavity. A novel method of signal analysis based on spectrum fitting has been developed to minimize the effect of baseline distrotions. Data are also presented on the relative response of alanine to 60Co gamma rays and high energy photons (4–12 MeV).
ISSN:0969-8043
1872-9800
DOI:10.1016/S0969-8043(96)00174-1