Uterine tumors resembling ovarian sex cord-stromal tumors: synchronous uterine tumors resembling ovarian sex cord-stromal tumors and ovarian sex cord tumor

Abstract Uterine tumors resembling ovarian sex cord-stromal tumors (UTROSCTs) are very rare. In this article, we present 3 cases that manifest classical histomorphological features alongside diverse immunohistochemical findings. As a distinctive finding, one of the patients had UTROSCT in the uterus...

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Bibliographic Details
Published in:Annals of diagnostic pathology 2010-12, Vol.14 (6), p.432-437
Main Authors: Abdullazade, Samir, MD, Kosemehmetoglu, Kemal, MD, Adanir, Ilknur, MD, Kutluay, Lale, MD, Usubutun, Alp, MD
Format: Article
Language:English
Subjects:
Adult
Calbindin 2
CD56 Antigen - metabolism
Desmin - metabolism
Diagnosis, Differential
Female
Granulosa cell tumor
Granulosa Cell Tumor - diagnosis
Granulosa Cell Tumor - metabolism
Granulosa Cell Tumor - pathology
Humans
Immunohistochemistry
Inhibins - metabolism
Middle Aged
Neoplasms, Multiple Primary - diagnosis
Neoplasms, Multiple Primary - metabolism
Neoplasms, Multiple Primary - pathology
Ovarian Neoplasms - diagnosis
Ovarian Neoplasms - metabolism
Ovarian Neoplasms - pathology
Pathology
S100 Calcium Binding Protein G - metabolism
Sex Cord-Gonadal Stromal Tumors - diagnosis
Sex Cord-Gonadal Stromal Tumors - metabolism
Sex Cord-Gonadal Stromal Tumors - pathology
Uterine Neoplasms - diagnosis
Uterine Neoplasms - metabolism
Uterine Neoplasms - pathology
Uterus
UTROSCT
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Summary:Abstract Uterine tumors resembling ovarian sex cord-stromal tumors (UTROSCTs) are very rare. In this article, we present 3 cases that manifest classical histomorphological features alongside diverse immunohistochemical findings. As a distinctive finding, one of the patients had UTROSCT in the uterus and an ovarian sex cord tumor, called granulosa cell tumor , in the left ovary, simultaneously. Problems in diagnosing such pathologic condition generally arise because of the variable histologic picture of UTROSCT and may cause problems for general and other nongynecologic surgical pathologists. Immunohistochemically, these tumors express different markers that indicate their polyphenotypic origins.
ISSN:1092-9134
1532-8198
DOI:10.1016/j.anndiagpath.2010.07.001