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Novel structure of the cellular mannan of the pathogenic yeast Candida krusei

On the basis of methylation analysis, 13C- and 1H-n.m.r. spectroscopic data, and the results of immunological methods, a new structure for the cell-wall α- d-mannan of the pathogenic yeast Candida krusei is proposed. In contrast to the α- d-mannans of other pathogenic yeasts of the Candida species,...

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Bibliographic Details
Published in:Carbohydrate research 1988-12, Vol.184, p.171-182
Main Authors: Kogan, Grigorij, Pavliak, Viliam, Šandula, Jozef, Masler, Ladislav
Format: Article
Language:English
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Summary:On the basis of methylation analysis, 13C- and 1H-n.m.r. spectroscopic data, and the results of immunological methods, a new structure for the cell-wall α- d-mannan of the pathogenic yeast Candida krusei is proposed. In contrast to the α- d-mannans of other pathogenic yeasts of the Candida species, which have (1→6)-linked main chains and many (1→2)- and/or (1→3)-linked side chains, the C. krusei mannan is lightly branched and contains (1→2) and (1→6) linkages in the ratio 3:1.
ISSN:0008-6215
1873-426X
DOI:10.1016/0008-6215(88)80015-6