Severe respiratory depression in the obstetric patient after intrathecal meperidine or sufentanil

Two cases of severe respiratory depression in the obstetric population are presented. The first occurred after intrathecal injection of a modest dose (50 mg) of meperidine. The second followed intrathecal administration of 10 μg of sufentanil after intravenous fentanyl. These cases illustrate the po...

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Bibliographic Details
Published in:International journal of obstetric anesthesia 1997-07, Vol.6 (3), p.182-184
Main Authors: Jaffee, J.B., Drease, G.E., Kelly, T., Newman, L.M.
Format: Article
Language:English
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Summary:Two cases of severe respiratory depression in the obstetric population are presented. The first occurred after intrathecal injection of a modest dose (50 mg) of meperidine. The second followed intrathecal administration of 10 μg of sufentanil after intravenous fentanyl. These cases illustrate the potential gravity of this complication and highlight the need for caution when giving intrathecal opioid following parenteral opioid administration.
ISSN:0959-289X
1532-3374
DOI:10.1016/S0959-289X(97)80086-6