Pharyngo-esophageal dysphagia in Parkinson's disease

The radiologic characteristics of pharyngoesophageal (PE) dysfunction in Parkinson's disease (PD) are not well established, partly because most previous studies have examined only small numbers of patients. We administered a dynamic videofluoroscopic swallowing function study to 71 patients wit...

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Bibliographic Details
Published in:Dysphagia 1997, Vol.12 (1), p.11-18
Main Authors: Leopold, N A, Kagel, M C
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cineradiography
Deglutition
Deglutition Disorders - diagnostic imaging
Deglutition Disorders - etiology
Deglutition Disorders - physiopathology
Dentistry
Esophageal Diseases - diagnostic imaging
Esophageal Diseases - etiology
Esophageal Diseases - physiopathology
Esophagus - physiopathology
Female
Fluoroscopy
Foreign Bodies
Gastric Emptying
Gastroesophageal Reflux - etiology
Gastroesophageal Reflux - physiopathology
Glottis - physiopathology
Humans
Male
Middle Aged
Muscle Contraction
Parkinson Disease - complications
Parkinson Disease - physiopathology
Parkinson's disease
Peristalsis
Pharyngeal Diseases - diagnostic imaging
Pharyngeal Diseases - etiology
Pharyngeal Diseases - physiopathology
Pharynx - physiopathology
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Summary:The radiologic characteristics of pharyngoesophageal (PE) dysfunction in Parkinson's disease (PD) are not well established, partly because most previous studies have examined only small numbers of patients. We administered a dynamic videofluoroscopic swallowing function study to 71 patients with idiopathic PD. Using the Hoehn and Yahr disease severity scale, patients were subdivided into those with mild/moderate disease, subgroup I (n = 38), and advanced PD disease, subgroup II (n = 33). From pharyngeal ingestion to gastric emptying, bolus transport was normal in only 2 patients. The most common abnormalities occurring during pharyngeal ingestion included impaired motility, vallecular and pyriform sinus stasis, supraglottic and glottic aspiration, and deficient epiglottic positioning and range of motion. Esophageal abnormalities were multiple but most commonly included delayed transport, stasis, bolus redirection, and tertiary contractions. Typical aberrations of lower esophageal sphincter (LES) function included an open or delayed opening of the LES and gastro-esophageal reflux. A pathogenesis linking PE with the pathology of PD is proposed.
ISSN:0179-051X
1432-0460
DOI:10.1007/PL00009512