Delayed onset of inflammatory nodules following hay fever desensitization injections

Summary Immediate anaphylaxis, short‐lived local reactions and occasionally tender nodules lasting for several years have all been described after desensitization injections for hay fever. We report two patients who developed painful nodules at injection sites several years after desensitization. Un...

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Bibliographic Details
Published in:Clinical and experimental dermatology 1988-11, Vol.13 (6), p.376-378
Main Authors: JONES, S.K., LOVELL, C.R., PEACHEY, R.D.G.
Format: Article
Language:English
Subjects:
Adult
Allergic diseases
Biological and medical sciences
Desensitization, Immunologic
Female
Humans
Immunopathology
Inflammation - etiology
Male
Medical sciences
Middle Aged
Rhinitis, Allergic, Seasonal - prevention & control
Skin allergic diseases. Stinging insect allergies
Time Factors
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Summary:Summary Immediate anaphylaxis, short‐lived local reactions and occasionally tender nodules lasting for several years have all been described after desensitization injections for hay fever. We report two patients who developed painful nodules at injection sites several years after desensitization. Unlike previous reports, it would seem that this is not related to the aluminium content of the injections and may be a local reaction to late release of antigen iu pollen. These late reactions add a further complication to the use of desensitization injections.
ISSN:0307-6938
1365-2230
DOI:10.1111/j.1365-2230.1988.tb00731.x