EARLY COGNITIVE MARKERS OF THE INCIDENCE OF DEMENTIA AND MORTALITY: A LONGITUDINAL POPULATION-BASED STUDY OF THE OLDEST OLD

This study examines whether cognitive markers at prior examinations are indicative of subsequent dementia and mortality. The sample was composed of subjects aged 84–90 at baseline who were reexamined three times over a 6‐year period on a comprehensive biobehavioral battery. Dementia was evaluated at...

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Bibliographic Details
Published in:International journal of geriatric psychiatry 1997-01, Vol.12 (1), p.53-59
Main Authors: JOHANSSON, BOO, ZARIT, STEVEN H.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Biomarkers
Cognition
cognitive performance
Dementia - diagnosis
Dementia - mortality
Geriatric Assessment
Geriatrics
Humans
Incidence
incidence of dementia
Longitudinal Studies
Medical sciences
Mental Status Schedule
mortality
Neuropsychological Tests
oldest old
Population Surveillance
Prognosis
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Sweden - epidemiology
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Summary:This study examines whether cognitive markers at prior examinations are indicative of subsequent dementia and mortality. The sample was composed of subjects aged 84–90 at baseline who were reexamined three times over a 6‐year period on a comprehensive biobehavioral battery. Dementia was evaluated at each examination using DSM–III‐R criteria. Results indicated that incident cases of dementia had lower cognitive scores both 2 and 4 years prior to diagnosis, compared to non‐demented survivors. Evidence for terminal decline was also found, as people who subsequently died also had lower cognitive performance at prior examinations, compared to non‐demented survivors. The findings suggest that mild cognitive dysfunction is an important clinical finding among the oldest old and may herald either the onset of dementia or mortality. © 1997 by John Wiley & Sons, Ltd.
ISSN:0885-6230
1099-1166
DOI:10.1002/(SICI)1099-1166(199701)12:1<53::AID-GPS507>3.0.CO;2-M