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Progressive multifocal leukoencephalopathy in an HIV-infected child

A child with perinatally acquired HIV infection presented with acute neurologic deterioration. A cerebellar white matter lesion seen on CT and MRI later proved to be progressive multifocal leukoencephalopathy (PML) by histology. Although a recognized disease of HIV-infected adults, PML is certain to...

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Published in:	Neuroradiology 1997-02, Vol.39 (2), p.142-144
Main Authors:	MORRISS, M. C, RUTSTEIN, R. M, RUDY, B, DESROCHERS, C, HUNTER, J. V, ZIMMERMAN, R. A
Format:	Article
Language:	English
Subjects:	AIDS Dementia Complex - diagnosis AIDS Dementia Complex - pathology AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - pathology AIDS/HIV Biological and medical sciences Biopsy Brain - pathology Child Diagnosis, Differential Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Leukoencephalopathy, Progressive Multifocal - diagnosis Leukoencephalopathy, Progressive Multifocal - pathology Magnetic Resonance Imaging Male Medical sciences Neurologic Examination Tomography, X-Ray Computed
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creator	MORRISS, M. C RUTSTEIN, R. M RUDY, B DESROCHERS, C HUNTER, J. V ZIMMERMAN, R. A
description	A child with perinatally acquired HIV infection presented with acute neurologic deterioration. A cerebellar white matter lesion seen on CT and MRI later proved to be progressive multifocal leukoencephalopathy (PML) by histology. Although a recognized disease of HIV-infected adults, PML is certain to be seen with more frequency in HIV-infected children who are surviving longer as a result of improved medical care. Recognition of the clinical and radiographic manifestations is important because of the dismal prognosis.
doi_str_mv	10.1007/s002340050383
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subjects	AIDS Dementia Complex - diagnosis AIDS Dementia Complex - pathology AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - pathology AIDS/HIV Biological and medical sciences Biopsy Brain - pathology Child Diagnosis, Differential Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Leukoencephalopathy, Progressive Multifocal - diagnosis Leukoencephalopathy, Progressive Multifocal - pathology Magnetic Resonance Imaging Male Medical sciences Neurologic Examination Tomography, X-Ray Computed
title	Progressive multifocal leukoencephalopathy in an HIV-infected child
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