Urinary Tract Infections: From Pathogenesis to Treatment

Community-acquired urinary tract infections occur in four major risk groups: in school-age girls, in young women in their sexually active years, in males with prostatic obstruction, and in the elderly. This review focuses on infections occurring in young women between late adolescence and the mid-fo...

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Bibliographic Details
Published in:Journal of Infectious Diseases 1989-03, Vol.159 (3), p.400-406
Main Authors: Stamm, Walter E., Hooton, Thomas M., Johnson, James R., Johnson, Carolyn, Stapleton, Ann, Roberts, Pacita L., Moseley, Steve L., Fihn, Stephan D.
Format: Article
Language:English
Subjects:
Adult
Annual Meeting Presentations
Antimicrobials
Contraceptive Devices, Female - adverse effects
Cystitis
Cystitis - etiology
Cystitis - therapy
Escherichia coli - pathogenicity
Female
Flora
Humans
Infections
Pyelonephritis
Pyelonephritis - etiology
Pyelonephritis - therapy
Sex
Urinary tract
Urinary tract infections
Urinary Tract Infections - etiology
Urinary Tract Infections - therapy
Vaginal diaphragms
Vaginitis - complications
Virulence factors
Women
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Summary:Community-acquired urinary tract infections occur in four major risk groups: in school-age girls, in young women in their sexually active years, in males with prostatic obstruction, and in the elderly. This review focuses on infections occurring in young women between late adolescence and the mid-forties. Six to seven million office visits annually in the United States are made because of acute uncomplicated urinary tract infections in this group, resulting in frequent time lost from work. 250,000 of these infections present as acute pyelonephritis, which often necessitates hospitalization and initial parenteral antimicrobial therapy. In 20% of women, frequent recurrences of infection follow the initial episode, producing additional morbidity and time lost from work. Both maternal and infant morbidity may occur in women who suffer infections during pregnancy.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/159.3.400