Thrombotic thrombocytopenic purpura: A treatable cause of childhood encephalopathy

We describe two patients less than 13 years of age with thrombotic thrombocytopenic purpura, a rare disorder in childhood. Both children were treated with plasma exchange therapy, which resulted in a rapid resolution of symptoms. This disorder is a cause of childhood encephalopathy, which can be tre...

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Bibliographic Details
Published in:The Journal of pediatrics 1997-02, Vol.130 (2), p.313-316
Main Authors: Lawlor, E.R., Webb, D.W.M., Hill, A., Wadsworth, L.D.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain Diseases - diagnosis
Brain Diseases - etiology
Brain Diseases - therapy
Child
Combined Modality Therapy
Hematologic and hematopoietic diseases
Humans
Male
Medical sciences
Plasma Exchange
Platelet diseases and coagulopathies
Purpura, Thrombotic Thrombocytopenic - complications
Purpura, Thrombotic Thrombocytopenic - diagnosis
Purpura, Thrombotic Thrombocytopenic - therapy
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Summary:We describe two patients less than 13 years of age with thrombotic thrombocytopenic purpura, a rare disorder in childhood. Both children were treated with plasma exchange therapy, which resulted in a rapid resolution of symptoms. This disorder is a cause of childhood encephalopathy, which can be treated effectively with plasma exchange.(J Pediatr 1997;130:313-6)
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(97)70362-7