The Correlation Between Pharmacodynamics and Pharmacokinetics: Basics of Pharmacokinetics-Pharmacodynamics Modeling

This article gives an introduction to the combination of drug transports and drug action in a body system. With the law of mass action, the Emax model has been deduced as the basis of correlation between pharmacokinetics and pharmacodynamics.

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Bibliographic Details
Published in:Journal of clinical pharmacology 1997-01, Vol.37 (S1), p.65S-69S
Main Authors: Cawello, Willi, Antonucci, Tammy
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
General pharmacology
Humans
Medical sciences
Models, Biological
Pharmacokinetics
Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
Pharmacology - methods
Pharmacology. Drug treatments
Receptors, Drug - drug effects
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Description
Summary:This article gives an introduction to the combination of drug transports and drug action in a body system. With the law of mass action, the Emax model has been deduced as the basis of correlation between pharmacokinetics and pharmacodynamics.
ISSN:0091-2700
1552-4604
DOI:10.1177/009127009703700124