A placebo-controlled trial verifying the efficacy of milrinone in weaning high-risk patients from cardiopulmonary bypass

Objective : to establish the efficacy of the phosphodiesterase inhibitor milrinone in facilitating weaning from cardiopulmonary bypass of high-risk patients with left ventricular dysfunction and/or pulmonary hypertension. Design : A double-blinded, placebo-controlled longitudinal study. Setting : A...

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Bibliographic Details
Published in:Journal of cardiothoracic and vascular anesthesia 1997-02, Vol.11 (1), p.37-41
Main Authors: Doolan, Lawrence A., Jones, Elizabeth F., Kalman, Jonathan, Buxton, Brian F., Tonkin, Andrew M.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
cardiac surgery
Cardiopulmonary Bypass
Cardiotonic agents
Cardiotonic Agents - administration & dosage
Cardiovascular system
Female
Hemodynamics
Humans
Male
Medical sciences
Middle Aged
Milrinone
Pharmacology. Drug treatments
Phosphodiesterase Inhibitors - administration & dosage
positive inotropic agents
Pyridones - administration & dosage
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Description
Summary:Objective : to establish the efficacy of the phosphodiesterase inhibitor milrinone in facilitating weaning from cardiopulmonary bypass of high-risk patients with left ventricular dysfunction and/or pulmonary hypertension. Design : A double-blinded, placebo-controlled longitudinal study. Setting : A university teaching hospital. Participants : Thirty-two patients with preoperative left ventricular ejection fraction
ISSN:1053-0770
1532-8422
DOI:10.1016/S1053-0770(97)90250-0