Transcoronary chemical ablation of ventricular tachycardia

After identification of the artery supplying blood to the arrhythmogenic area, transcoronary chemical ablation of ventricular tachycardia was undertaken in three patients with incessant tachycardia in whom the other therapeutic options had failed. Sterile ethanol (96%) was given at a dose of 1.5 ml...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1989-03, Vol.79 (3), p.475-482
Main Authors: BRUGADA, P, DE SWART, H, SMEETS, J. L. R. M, WELLENS, H. J. J
Format: Article
Language:English
Subjects:
Adult
Angiography
Biological and medical sciences
Cardiac Catheterization
Cardiac dysrhythmias
Cardiology. Vascular system
Collateral Circulation
Coronary Circulation
Coronary Vessels
Ethanol - administration & dosage
Heart
Humans
Male
Medical sciences
Middle Aged
Myocardial Infarction - complications
Tachycardia - etiology
Tachycardia - therapy
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Summary:After identification of the artery supplying blood to the arrhythmogenic area, transcoronary chemical ablation of ventricular tachycardia was undertaken in three patients with incessant tachycardia in whom the other therapeutic options had failed. Sterile ethanol (96%) was given at a dose of 1.5 ml in two patients and a total of 6 ml in the third. The arrhythmia was cured in two patients and suppressed during a 1-month period in the third until new collateral blood supply to the arrhythmogenic area developed and ventricular tachycardia recurred. The procedure was then repeated successfully. After administration of ethanol in the high interventricular septum, one patient developed temporary complete atrioventricular block and a pacemaker was implanted. No other complications occurred. We observed that in patients with ventricular tachycardia after myocardial infarction, it is possible to identify and catheterize small coronary arteries responsible for blood supply to the site of origin or pathway of ventricular tachycardia. After careful transcoronary mapping with saline, chemical ablation can prevent further episodes of the arrhythmia in selected patients.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.cir.79.3.475