The glutathione S-transferases: an update

Over the last 15 years, we have passed through an initial period in which multiple forms of GST in various organs and different species were identified and characterized. The focus of current research is to define the role of the numerous isozymes in cell function, to ascertain the relationship betw...

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Bibliographic Details
Published in:Hepatology (Baltimore, Md.) Md.), 1989-03, Vol.9 (3), p.486-496
Main Author: Boyer, T D
Format: Article
Language:English
Subjects:
Animals
Carrier Proteins - metabolism
Enzyme Induction
Glutathione Transferase - genetics
Glutathione Transferase - metabolism
Glutathione Transferase - physiology
Humans
Intracellular Membranes - metabolism
Molecular Biology
Terminology as Topic
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Summary:Over the last 15 years, we have passed through an initial period in which multiple forms of GST in various organs and different species were identified and characterized. The focus of current research is to define the role of the numerous isozymes in cell function, to ascertain the relationship between structure and function of different isozymes and to determine how the expression of GST is regulated in different tissues. During these studies, it is expected that new roles for the GST will be proposed, and this family of multifunctional proteins will continue to hold the interest of numerous investigators for many years.
ISSN:0270-9139
DOI:10.1002/hep.1840090324