Candida glabrata chorioamnionitis following in vitro fertilization and embryo transfer

Candida glabrata is a yeast which is considered to be a commensal of the vagina with limited pathogenicity in the immunocompetent host. We report 2 cases of severe chorioamnionitis occurring in pregnancies achieved by in vitro fertilization techniques which resulted in preterm delivery and pregnancy...

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Bibliographic Details
Published in:Australian & New Zealand journal of obstetrics & gynaecology 1997-02, Vol.37 (1), p.88-91
Main Authors: Sfameni, S F, Talbot, J M, Chow, S L, Brenton, L A, Scurry, J P
Format: Article
Language:English
Subjects:
Adult
Candidiasis - etiology
Chorioamnionitis - etiology
Chorioamnionitis - microbiology
Embryo Transfer - adverse effects
Female
Fertilization in Vitro - adverse effects
Fetal Death
Humans
Obstetric Labor, Premature - microbiology
Pregnancy
Pregnancy, Multiple
Triplets
Twins
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Summary:Candida glabrata is a yeast which is considered to be a commensal of the vagina with limited pathogenicity in the immunocompetent host. We report 2 cases of severe chorioamnionitis occurring in pregnancies achieved by in vitro fertilization techniques which resulted in preterm delivery and pregnancy loss. Candida glabrata as the causative agent was probably introduced into the uterus by the cannula at the time of embryo transfer. It is recommended that appropriate investigation of the microbial flora of the cervix be undertaken and treatment instituted prior to embryo transfer in order to prevent this complication.
ISSN:0004-8666
DOI:10.1111/j.1479-828X.1997.tb02225.x