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Middle Ear Pressure Variation: Effect of Nitrous Oxide
Previous studies examining middle ear pressure changes due to inhalant anesthesia, including nitrous oxide, have cited equivocal results. An investigation was performed to closely monitor changes in middle ear pressure during middle ear surgery. Baseline tympanometry was performed before anesthesia,...
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| Published in: | The Laryngoscope 1997-03, Vol.107 (3), p.357-363 |
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| Language: | English |
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| container_end_page | 363 |
| container_issue | 3 |
| container_start_page | 357 |
| container_title | The Laryngoscope |
| container_volume | 107 |
| creator | Chinn, Kathleen Brown, Orval E. Manning, Scott C. Crandell, Carl C. |
| description | Previous studies examining middle ear pressure changes due to inhalant anesthesia, including nitrous oxide, have cited equivocal results. An investigation was performed to closely monitor changes in middle ear pressure during middle ear surgery. Baseline tympanometry was performed before anesthesia, and middle ear pressure was then documented in 1‐min time intervals. A total of 97 subjects were studied; 51 received nitrous oxide and halothane, and 46 received halothane alone. Results indicate that nitrous oxide causes significantly greater pressure fluctuations than halothane alone. There were no effects for time of surgery, type of fluid, or baseline. Pressure fluctuation was attributed to eustachian tube function. Case studies are presented to demonstrate subject variability, and suggestions for validation study procedures are presented. |
| doi_str_mv | 10.1097/00005537-199703000-00015 |
| format | article |
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An investigation was performed to closely monitor changes in middle ear pressure during middle ear surgery. Baseline tympanometry was performed before anesthesia, and middle ear pressure was then documented in 1‐min time intervals. A total of 97 subjects were studied; 51 received nitrous oxide and halothane, and 46 received halothane alone. Results indicate that nitrous oxide causes significantly greater pressure fluctuations than halothane alone. There were no effects for time of surgery, type of fluid, or baseline. Pressure fluctuation was attributed to eustachian tube function. Case studies are presented to demonstrate subject variability, and suggestions for validation study procedures are presented.</description><identifier>ISSN: 0023-852X</identifier><identifier>EISSN: 1531-4995</identifier><identifier>DOI: 10.1097/00005537-199703000-00015</identifier><identifier>PMID: 9121313</identifier><identifier>CODEN: LARYA8</identifier><language>eng</language><publisher>Hoboken, NJ: John Wiley & Sons, Inc</publisher><subject>Acoustic Impedance Tests ; Adenoidectomy ; Anesthetics, Inhalation - administration & dosage ; Anesthetics, Inhalation - pharmacology ; Biological and medical sciences ; Child ; Child, Preschool ; Ear, Middle - drug effects ; Ear, Middle - physiology ; Ear, Middle - surgery ; Eustachian Tube - drug effects ; Eustachian Tube - physiology ; Female ; Halothane ; Halothane - administration & dosage ; Halothane - pharmacology ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Humans ; Infant ; Inhalant anesthesia ; Male ; Medical sciences ; Middle ear pressure changes ; Middle ear surgery ; Middle Ear Ventilation ; Monitoring, Intraoperative ; Nitrous oxide ; Nitrous Oxide - administration & dosage ; Nitrous Oxide - pharmacology ; Otitis Media - physiopathology ; Otitis Media - surgery ; Pressure ; Reproducibility of Results ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the ear, the auditive nerve and the facial nerve ; Time Factors ; Tonsillectomy ; Tympanic Membrane - surgery</subject><ispartof>The Laryngoscope, 1997-03, Vol.107 (3), p.357-363</ispartof><rights>Copyright © 1997 The Triological Society</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4385-796fcbe018adbbfd23573fbe949c1a6fa2f230c7372d47c84819ae70aa58c2f63</citedby><cites>FETCH-LOGICAL-c4385-796fcbe018adbbfd23573fbe949c1a6fa2f230c7372d47c84819ae70aa58c2f63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2628394$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9121313$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chinn, Kathleen</creatorcontrib><creatorcontrib>Brown, Orval E.</creatorcontrib><creatorcontrib>Manning, Scott C.</creatorcontrib><creatorcontrib>Crandell, Carl C.</creatorcontrib><title>Middle Ear Pressure Variation: Effect of Nitrous Oxide</title><title>The Laryngoscope</title><addtitle>The Laryngoscope</addtitle><description>Previous studies examining middle ear pressure changes due to inhalant anesthesia, including nitrous oxide, have cited equivocal results. An investigation was performed to closely monitor changes in middle ear pressure during middle ear surgery. Baseline tympanometry was performed before anesthesia, and middle ear pressure was then documented in 1‐min time intervals. A total of 97 subjects were studied; 51 received nitrous oxide and halothane, and 46 received halothane alone. Results indicate that nitrous oxide causes significantly greater pressure fluctuations than halothane alone. There were no effects for time of surgery, type of fluid, or baseline. Pressure fluctuation was attributed to eustachian tube function. Case studies are presented to demonstrate subject variability, and suggestions for validation study procedures are presented.</description><subject>Acoustic Impedance Tests</subject><subject>Adenoidectomy</subject><subject>Anesthetics, Inhalation - administration & dosage</subject><subject>Anesthetics, Inhalation - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Ear, Middle - drug effects</subject><subject>Ear, Middle - physiology</subject><subject>Ear, Middle - surgery</subject><subject>Eustachian Tube - drug effects</subject><subject>Eustachian Tube - physiology</subject><subject>Female</subject><subject>Halothane</subject><subject>Halothane - administration & dosage</subject><subject>Halothane - pharmacology</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Humans</subject><subject>Infant</subject><subject>Inhalant anesthesia</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle ear pressure changes</subject><subject>Middle ear surgery</subject><subject>Middle Ear Ventilation</subject><subject>Monitoring, Intraoperative</subject><subject>Nitrous oxide</subject><subject>Nitrous Oxide - administration & dosage</subject><subject>Nitrous Oxide - pharmacology</subject><subject>Otitis Media - physiopathology</subject><subject>Otitis Media - surgery</subject><subject>Pressure</subject><subject>Reproducibility of Results</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the ear, the auditive nerve and the facial nerve</subject><subject>Time Factors</subject><subject>Tonsillectomy</subject><subject>Tympanic Membrane - surgery</subject><issn>0023-852X</issn><issn>1531-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNqNkF1PwyAUhonR6Kz-BJNeGO-qfJQC3pm5TZPpzOL3DaEUErRbJ3TR_XvRzV5LQgic97zn5QEgRfAUQcHOYFyUEpYhIRgk8ZbFjegW6CFKUJYLQbdBD0JMMk7x8x7YD-EtKhihcBfsCoQRQaQHihtXVbVJB8qnd96EsPQmfVTeqdY18_N0YK3RbdrY9Na1vlmGdPLlKnMAdqyqgzncnAl4GA7u-1fZeDK67l-MM50TTjMmCqtLAxFXVVnaChPKiC2NyIVGqrAKW0ygZoThKmea5xwJZRhUinKNbUEScLL2XfjmY2lCK2cuaFPXam5iGMk4FzmJf0kAXwu1b0LwxsqFdzPlVxJB-YNM_iGTHTL5iyy2Hm1mLMuZqbrGDaNYP97UVdCqtl7NtQudDBeYkxgiAZdr2aerzerf4-X4YvpCaY5gfP1Nk61tXGjNV2ej_LssIicqn25HMp8OxfNrfygfyTcCe5PR</recordid><startdate>199703</startdate><enddate>199703</enddate><creator>Chinn, Kathleen</creator><creator>Brown, Orval E.</creator><creator>Manning, Scott C.</creator><creator>Crandell, Carl C.</creator><general>John Wiley & Sons, Inc</general><general>Wiley-Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>199703</creationdate><title>Middle Ear Pressure Variation: Effect of Nitrous Oxide</title><author>Chinn, Kathleen ; Brown, Orval E. ; Manning, Scott C. ; Crandell, Carl C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4385-796fcbe018adbbfd23573fbe949c1a6fa2f230c7372d47c84819ae70aa58c2f63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Acoustic Impedance Tests</topic><topic>Adenoidectomy</topic><topic>Anesthetics, Inhalation - administration & dosage</topic><topic>Anesthetics, Inhalation - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Ear, Middle - drug effects</topic><topic>Ear, Middle - physiology</topic><topic>Ear, Middle - surgery</topic><topic>Eustachian Tube - drug effects</topic><topic>Eustachian Tube - physiology</topic><topic>Female</topic><topic>Halothane</topic><topic>Halothane - administration & dosage</topic><topic>Halothane - pharmacology</topic><topic>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</topic><topic>Humans</topic><topic>Infant</topic><topic>Inhalant anesthesia</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle ear pressure changes</topic><topic>Middle ear surgery</topic><topic>Middle Ear Ventilation</topic><topic>Monitoring, Intraoperative</topic><topic>Nitrous oxide</topic><topic>Nitrous Oxide - administration & dosage</topic><topic>Nitrous Oxide - pharmacology</topic><topic>Otitis Media - physiopathology</topic><topic>Otitis Media - surgery</topic><topic>Pressure</topic><topic>Reproducibility of Results</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. 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An investigation was performed to closely monitor changes in middle ear pressure during middle ear surgery. Baseline tympanometry was performed before anesthesia, and middle ear pressure was then documented in 1‐min time intervals. A total of 97 subjects were studied; 51 received nitrous oxide and halothane, and 46 received halothane alone. Results indicate that nitrous oxide causes significantly greater pressure fluctuations than halothane alone. There were no effects for time of surgery, type of fluid, or baseline. Pressure fluctuation was attributed to eustachian tube function. Case studies are presented to demonstrate subject variability, and suggestions for validation study procedures are presented.</abstract><cop>Hoboken, NJ</cop><pub>John Wiley & Sons, Inc</pub><pmid>9121313</pmid><doi>10.1097/00005537-199703000-00015</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0023-852X |
| ispartof | The Laryngoscope, 1997-03, Vol.107 (3), p.357-363 |
| issn | 0023-852X 1531-4995 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78894321 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Acoustic Impedance Tests Adenoidectomy Anesthetics, Inhalation - administration & dosage Anesthetics, Inhalation - pharmacology Biological and medical sciences Child Child, Preschool Ear, Middle - drug effects Ear, Middle - physiology Ear, Middle - surgery Eustachian Tube - drug effects Eustachian Tube - physiology Female Halothane Halothane - administration & dosage Halothane - pharmacology Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Humans Infant Inhalant anesthesia Male Medical sciences Middle ear pressure changes Middle ear surgery Middle Ear Ventilation Monitoring, Intraoperative Nitrous oxide Nitrous Oxide - administration & dosage Nitrous Oxide - pharmacology Otitis Media - physiopathology Otitis Media - surgery Pressure Reproducibility of Results Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the ear, the auditive nerve and the facial nerve Time Factors Tonsillectomy Tympanic Membrane - surgery |
| title | Middle Ear Pressure Variation: Effect of Nitrous Oxide |
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