L-671, 329, A NEW ANTIFUNGAL AGENT: II. STRUCTURE DETERMINATION

Based on spectroscopic data L-671, 329, isolated from a filamentous fungus ATCC 20868, has been assigned the structure 1. The compound is a lipopeptide antifungal agent and a structural analog of echinocandin B.

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Bibliographic Details
Published in:Journal of antibiotics 1989/02/25, Vol.42(2), pp.168-173
Main Authors: WICHMANN, CAROL F., LIESCH, JERROLD M., SCHWARTZ, ROBERT E.
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Amino Acids - analysis
Anti-Bacterial Agents
Antibiotics (antibacterial agents, antifungal agents)
Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents
Antifungal Agents
Applied microbiology
Biological and medical sciences
echinocandin
Echinocandins
Fundamental and applied biological sciences. Psychology
Fungal Proteins
Gas Chromatography-Mass Spectrometry
L-671,329
Magnetic Resonance Spectroscopy
Mass Spectrometry
Microbiology
Molecular Structure
Peptides
Peptides, Cyclic
Spectrophotometry, Ultraviolet
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Description
Summary:Based on spectroscopic data L-671, 329, isolated from a filamentous fungus ATCC 20868, has been assigned the structure 1. The compound is a lipopeptide antifungal agent and a structural analog of echinocandin B.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.42.168