L-671, 329, A NEW ANTIFUNGAL AGENT: I. FERMENTATION AND ISOLATION

In screening for new antifungal agents from fungi, a new lipopeptide antifungal agent, L-671, 329, similar to echinocandin B, has been isolated from Zalerion arboricola. Studies indicate that L-671, 329 is produced under both solid and liquid fermentation conditions.

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Bibliographic Details
Published in:Journal of antibiotics 1989/02/25, Vol.42(2), pp.163-167
Main Authors: SCHWARTZ, ROBERT E., GIACOBBE, ROBERT A., BLAND, JUDITH A., MONAGHAN, RICHARD L.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Antibiotics (antibacterial agents, antifungal agents)
Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents
antifungal agents
Antifungal Agents - isolation & purification
Antifungal Agents - pharmacology
Applied microbiology
Biological and medical sciences
Candida albicans - drug effects
Candida albicans - growth & development
Chromatography, High Pressure Liquid
Echinocandins
Fermentation
Fundamental and applied biological sciences. Psychology
lipoproteins
Microbiology
peptide antibiotics
Peptides
Peptides, Cyclic - isolation & purification
Peptides, Cyclic - pharmacology
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Description
Summary:In screening for new antifungal agents from fungi, a new lipopeptide antifungal agent, L-671, 329, similar to echinocandin B, has been isolated from Zalerion arboricola. Studies indicate that L-671, 329 is produced under both solid and liquid fermentation conditions.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.42.163