Effect of Fibronectin on C3b and Fc Receptor-mediated Phagocytosis by Peripheral Blood Monocytes in Uraemic Patients

The influence of human fibronectin was evaluated on the phagocytosis in vitro of C. albicans (C3b receptor-mediated) and IgG antibody-coated sheep erythrocytes .(Fc receptor-mediated) by the peripheral blood monocytes of 40 uraemic patients undergoing periodic haemodialysis. Some nutritional paramet...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1989, Vol.4 (1), p.15-20
Main Authors: Pertosa, G., Mastrolitti, R.T., Späth, P.J., Fracasso, A.R., Manno, C., Schena, F.P.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Cells, Cultured
Complement C3 - metabolism
Complement C4 - metabolism
Female
Fibronectin
Fibronectins - blood
Haemodialysis
Humans
Immunoglobulin G - metabolism
Infections
Male
Malnutrition
Medical sciences
Middle Aged
Monocytes - physiology
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Phagocytosis
Receptors, Complement - physiology
Receptors, Complement 3b
Receptors, Fc - physiology
Renal Dialysis - adverse effects
Renal failure
Serum Albumin - metabolism
Uremia - blood
Uremia - physiopathology
Weight Loss
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Summary:The influence of human fibronectin was evaluated on the phagocytosis in vitro of C. albicans (C3b receptor-mediated) and IgG antibody-coated sheep erythrocytes .(Fc receptor-mediated) by the peripheral blood monocytes of 40 uraemic patients undergoing periodic haemodialysis. Some nutritional parameters (albumin, transferrin, C4, C3, haematocrit, lymphocyte count, height and bodyweight) were also evaluated. Results showed significantly decreased plasma fibronectin (P
ISSN:0931-0509
1460-2385
1460-2385
DOI:10.1093/oxfordjournals.ndt.a091772