Cranial MRI findings in myotonic dystrophy

MRI was performed in 13 patients with the adult form of myotonic dystrophy (MD) and compared with that of sex- and age-matched normal controls. There was some cerebral atrophy in the patients and marked thickening of the skull in three of them, associated with ossification of the falx cerebri in two...

Full description

Saved in:
Bibliographic Details
Published in:Neuroradiology 1997-03, Vol.39 (3), p.166-170
Main Authors: MIAUX, Y, CHIRAS, J, EYMARD, B, LAURIOT-PREVOST, M. C, RADVANYI, H, MARTIN-DUVERNEUIL, N, DELAPORTE, C
Format: Article
Language:English
Subjects:
Adult
Atrophy
Biological and medical sciences
Brain - pathology
Cerebral Cortex - pathology
Diseases of striated muscles. Neuromuscular diseases
Female
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Myotonic Dystrophy - diagnosis
Neurologic Examination
Neurology
Ossification, Heterotopic - diagnosis
Skull - pathology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:MRI was performed in 13 patients with the adult form of myotonic dystrophy (MD) and compared with that of sex- and age-matched normal controls. There was some cerebral atrophy in the patients and marked thickening of the skull in three of them, associated with ossification of the falx cerebri in two. We found high-signal areas on T2-weighted images in the white matter in 9 (70%) of the patients; five showed high-signal areas in the subcortical white matter of the temporal lobes. These findings were associated with intellectual impairment in only one patient, who had a history of a difficult birth and temporal lobe epilepsy.
ISSN:0028-3940
1432-1920
DOI:10.1007/s002340050385