RNA crystallography

The current state of three-dimensional structure analysis of RNA by x-ray crystallography is summarized. The methods of sample preparation, crystallization, data collection, and structure solution are discussed, followed by a review of the RNA structures that have been determined and of common struc...

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Bibliographic Details
Published in:BIOPOLYMERS NUCLEIC ACID SCI 1997, Vol.44 (1), p.3-21
Main Authors: Holbrook, S.R, Kim, S.H
Format: Article
Language:English
Subjects:
Base Sequence
binding
catalytic RNA
chemical structure
crystal structure
Crystallography, X-Ray - methods
interactions
internal loop
literature reviews
metal ions
Models, Molecular
molecular conformation
Molecular Structure
Nucleic Acid Conformation
review
ribozyme
RNA
RNA - chemistry
RNA - isolation & purification
rna structure
rna-protein interactions
transfer
transfer RNA
x-ray crystallography
X-ray diffraction
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Description
Summary:The current state of three-dimensional structure analysis of RNA by x-ray crystallography is summarized. The methods of sample preparation, crystallization, data collection, and structure solution are discussed, followed by a review of the RNA structures that have been determined and of common structural features, and finally, an appraisal of future prospects for x-ray crystal structure analysis of RNA.
ISSN:0006-3525
1097-0282
DOI:10.1002/(SICI)1097-0282(1997)44:1<3::AID-BIP2>3.0.CO;2-Z