Drug discovery and development through the genetic engineering of antibiotic-producing microorganisms

This perspective examines one area - antibiotic discovery and production - where molecular biologists and medicinal chemists are collaborating to drive the quest for new drugs and to improve production of old ones.

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Bibliographic Details
Published in:Journal of medicinal chemistry 1989-05, Vol.32 (5), p.929-936
Main Authors: Hutchinson, C R, Borell, C W, Otten, S L, Stutzman-Engwall, K J, Wang, Y G
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - biosynthesis
Drug Design
Genetic Engineering
Streptomyces - genetics
Online Access:Get full text
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Description
Summary:This perspective examines one area - antibiotic discovery and production - where molecular biologists and medicinal chemists are collaborating to drive the quest for new drugs and to improve production of old ones.
ISSN:0022-2623
DOI:10.1021/jm00125a001