Hemodynamic ischemic stroke during carotid endarterectomy: An appraisal of risk and cerebral protection

The purpose of this study was to validate the commonly accepted indicators of risk of ischemic stroke that indicate the necessity for cerebral protection during carotid endarterectomy (CEA), and to examine the efficacy of high-dose thiopentone sodium (thiopental) as a cerebral protection method in p...

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Bibliographic Details
Published in:Journal of vascular surgery 1997-04, Vol.25 (4), p.611-619
Main Authors: Frawley, J.E., Hicks, R.G., Beaudoin, M., Woodey, R.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Blood Pressure
Brain Ischemia - etiology
Brain Ischemia - prevention & control
Carotid Arteries - pathology
Carotid Stenosis - pathology
Carotid Stenosis - surgery
Cerebrovascular Circulation - drug effects
Cerebrovascular Disorders - etiology
Cerebrovascular Disorders - prevention & control
Constriction
Electroencephalography
Endarterectomy, Carotid - adverse effects
Female
Hemodynamics
Humans
Intraoperative Complications - prevention & control
Male
Medical sciences
Middle Aged
Monitoring, Intraoperative
Neurologic Examination
Neuropharmacology
Neuroprotective agent
Neuroprotective Agents - administration & dosage
Neuroprotective Agents - therapeutic use
Pharmacology. Drug treatments
Prospective Studies
Reproducibility of Results
Risk Assessment
Risk Factors
Thiopental - administration & dosage
Thiopental - therapeutic use
Time Factors
Treatment Outcome
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Summary:The purpose of this study was to validate the commonly accepted indicators of risk of ischemic stroke that indicate the necessity for cerebral protection during carotid endarterectomy (CEA), and to examine the efficacy of high-dose thiopentone sodium (thiopental) as a cerebral protection method in patients who are at high risk of intraoperative ischemic stroke. In a prospective study of 37 CEAs performed for symptomatic stenosis >70%, functional and clinical indicators of risk of ischemic stroke during carotid cross-clamping were identified. Functional indicators of risk were the development of ischemic electroencephalogram (EEG) changes and stump pressure
ISSN:0741-5214
1097-6809
DOI:10.1016/S0741-5214(97)70286-6