Surface wettability enhancement of silicone hydrogel lenses by processing with polar plastic molds

In the quest for hydrogel contact lenses with improved extended wear capability, the use of siloxane moieties in the lens materials was investigated. However, the introduction of hydrophobic siloxane groups gave rise to wettability and lipidlike deposit problems. It was found that when polysiloxane‐...

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Bibliographic Details
Published in:Journal of biomedical materials research 1997-06, Vol.35 (3), p.349-356
Main Authors: Lai, Yu-Chin, Friends, Gary D.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Contact Lenses, Extended-Wear
Contact Lenses, Hydrophilic
Diseases of the eye
Humans
Hydrogel, Polyethylene Glycol Dimethacrylate
Materials Testing
Medical sciences
Patents as Topic
Plastics
Polyesters
Polyethylene Glycols
Polyvinyl Chloride
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Silicones
Surface Properties
United States
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Description
Summary:In the quest for hydrogel contact lenses with improved extended wear capability, the use of siloxane moieties in the lens materials was investigated. However, the introduction of hydrophobic siloxane groups gave rise to wettability and lipidlike deposit problems. It was found that when polysiloxane‐based compositions for hydrogels were processed with polar plastic molds, such as those fabricated from an acrylonitrile‐based polymer, the hydrogel lenses fabricated were wettable, with minimized lipidlike deposits. These findings were supported by the wettability of silicone hydrogel films, silicon, and nitrogen element contents near lens surfaces, as well as the results from clinical assessment of silicone hydrogel lenses. © 1997 John Wiley & Sons, Inc. J Biomed Mater Res, 35, 349–356, 1997.
ISSN:0021-9304
1097-4636
DOI:10.1002/(SICI)1097-4636(19970605)35:3<349::AID-JBM9>3.0.CO;2-H