Menopause-associated changes in plasma lipids, insulin-like growth factor I and blood pressure: a longitudinal study

We examined the effects of the menopause transition on plasma lipids, insulin‐like growth factor I (IGF‐I) and blood pressure. An initial cohort of 38, non‐smoking, healthy premenopausal women (44–48 years) were examined at baseline and after a 6‐year follow‐up period. At follow‐up, 18 women had spo...

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Bibliographic Details
Published in:European journal of clinical investigation 1997-04, Vol.27 (4), p.322-326
Main Authors: POEHLMAN, E. T., TOTH, M. J., ADES, P. A., ROSEN, C. J.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Blood Pressure
Body Weight
Cholesterol, HDL - blood
Cholesterol, LDL - blood
fat distribution
Female
Fundamental and applied biological sciences. Psychology
Humans
Insulin-Like Growth Factor I - analysis
lipid
Lipids - blood
Longitudinal Studies
menopause
Menopause - blood
Menopause - physiology
Middle Aged
Sexual differentiation and maturation. Puberty. Climacterium
Vertebrates: reproduction
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Summary:We examined the effects of the menopause transition on plasma lipids, insulin‐like growth factor I (IGF‐I) and blood pressure. An initial cohort of 38, non‐smoking, healthy premenopausal women (44–48 years) were examined at baseline and after a 6‐year follow‐up period. At follow‐up, 18 women had spontaneously stopped menstruating, whereas 17 women remained premenopausal. Women who experienced natural menopause showed a greater decline in high‐density lipoproteins (−5 ± 4 mg dL−1 vs. −1 ± 3 mg dL−1; P 
ISSN:0014-2972
1365-2362
DOI:10.1046/j.1365-2362.1997.1160662.x