Viral manipulations of the actin cytoskeleton

Viruses succeed as intracellular parasites because of their ability to invade cells and appropriate the cellular machinery required during their life cycle. The actin cytoskeleton of the host cell does not escape viral infection unscathed, but is often co-opted by the virus at many different stages...

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Bibliographic Details
Published in:Trends in microbiology (Regular ed.) 1997-04, Vol.5 (4), p.142-148
Main Authors: Cudmore, Sally, Reckmann, Inge, Way, Michael
Format: Article
Language:English
Subjects:
Actins - metabolism
Animals
Cytoskeleton - ultrastructure
Humans
Iridovirus - physiology
Nucleopolyhedrovirus - physiology
Respirovirus - physiology
Retroviridae - physiology
Vaccinia virus - physiology
Viral Proteins - metabolism
Virus Physiological Phenomena
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Summary:Viruses succeed as intracellular parasites because of their ability to invade cells and appropriate the cellular machinery required during their life cycle. The actin cytoskeleton of the host cell does not escape viral infection unscathed, but is often co-opted by the virus at many different stages of its life cycle to facilitate the infection process.
ISSN:0966-842X
1878-4380
DOI:10.1016/S0966-842X(97)01011-1