Sequence analysis of the lymphotropic aleutian disease parvovirus ADV-SL3

About 98% of the DNA sequence of the lymphotropic Aleutian disease parvovirus isolate ADV-SL3 was determined and analysed. The sequence revealed that this isolate was a type-1 ADV strain, supporting that the currently used typing of ADV viruses does not correlate with virulence or pathogenicity. ADV...

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Bibliographic Details
Published in:Archives of virology 1997, Vol.142 (1), p.157-166
Main Authors: SCHUIERER, S, BLOOM, M. E, KAADEN, O. R, TRUYEN, U
Format: Article
Language:English
Subjects:
Aleutian disease virus
Aleutian Mink Disease Virus - genetics
Amino Acid Sequence
Animals
Bacteriology
Biological and medical sciences
Capsid - genetics
Capsid Proteins
Fundamental and applied biological sciences. Psychology
Genetics
Genome, Viral
Microbiology
Mink
Molecular Sequence Data
Parvovirus
Phylogeny
Sequence Alignment
Sequence Analysis
Viral Nonstructural Proteins - genetics
Virology
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Description
Summary:About 98% of the DNA sequence of the lymphotropic Aleutian disease parvovirus isolate ADV-SL3 was determined and analysed. The sequence revealed that this isolate was a type-1 ADV strain, supporting that the currently used typing of ADV viruses does not correlate with virulence or pathogenicity. ADV-SL3 had a very high overall homology of 99.5% to the prototype strain ADV-G at the DNA level. Comparative sequence analyses with various ADV isolates of known virulence did not reveal a consensus sequence that could obviously be responsible for the apparently unique biological properties of this virus strain.
ISSN:0304-8608
1432-8798
DOI:10.1007/s007050050066