Treatment of infantile primary pulmonary hypertension by intravenous infusion of lipo-prostaglandin I2 analog

We used a new vasodilator, TTC-909 (a prostaglandin I2 analog incorporated in lipid microspheres), which produced marked reduction in the pulmonary arterial pressure and resistance in an infant with primary pulmonary hypertension.

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Bibliographic Details
Published in:The Journal of pediatrics 1997-05, Vol.130 (5), p.835-838
Main Authors: Takigiku, Kiyohiro, Shibata, Toshimitsu, Yasui, Kiyoshi, Iwamoto, Mari, Sagawa, Koichi, Yamaoka, Koji, Tsuda, Naoya
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Epoprostenol - analogs & derivatives
Epoprostenol - therapeutic use
Female
Hemodynamics - drug effects
Humans
Hypertension, Pulmonary - drug therapy
Infant
Infusions, Intravenous
Intensive care medicine
Medical sciences
Vasodilator Agents - therapeutic use
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Description
Summary:We used a new vasodilator, TTC-909 (a prostaglandin I2 analog incorporated in lipid microspheres), which produced marked reduction in the pulmonary arterial pressure and resistance in an infant with primary pulmonary hypertension.
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(97)80032-7