Overview of the yeast genome. [Erratum: June 12, 1997, v. 387 (6634), p. 737.]

The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism...

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Bibliographic Details
Published in:Nature (London) 1997-05, Vol.387 (6632S), p.7-65
Main Authors: Mewes, H.W, Albermann, K, Bahr, M, Frishman, D, Gleissner, A, Hani, J, Heumann, K, Kleine, K, Maierl, A, Oliver, S.G
Format: Article
Language:English
Subjects:
Chromosome Mapping
Databases, Factual
Fungal Proteins - genetics
Fungal Proteins - metabolism
genes
genome
Genome, Fungal
molecular biology
Multigene Family
Saccharomyces cerevisiae
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae - metabolism
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Summary:The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism. 12 million bases were sequenced in a truly international effort involving European, US, Canadian and Japanese laboratories. While me yeast genome represents only a small fraction of the information in today's public sequence databases, me complete, ordered and non-redundant sequence provides an invaluable resource for the detailed analysis of cellular gene function and genome architecture. In terms of throughput, completeness and information content, yeast has always been the lead eukaryotic organism in genomics; it is still the largest genome to be completely sequenced.
ISSN:0028-0836
1476-4687
DOI:10.1038/387s007