Heterobifunctional Cross-Linkers Containing 4,9-Dioxa-1,12-dodecanediamine Spacers

A series of heterobifunctional linker arms has been prepared by functionalization of (tert-butoxycarbonyl)-4,9-dioxa-1,12-dodecanediamine [tBOC-HN(CH2)3O(CH2)4O(CH2)3NH2] with anhydrides or acid chloride.

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Bibliographic Details
Published in:Bioconjugate chemistry 1997-05, Vol.8 (3), p.447-452
Main Authors: Johnson, Gary M, Albarella, James P, Petry, Christoph
Format: Article
Language:English
Subjects:
Antibodies, Monoclonal
Cross-Linking Reagents - chemical synthesis
Diamines
Immunoenzyme Techniques
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Description
Summary:A series of heterobifunctional linker arms has been prepared by functionalization of (tert-butoxycarbonyl)-4,9-dioxa-1,12-dodecanediamine [tBOC-HN(CH2)3O(CH2)4O(CH2)3NH2] with anhydrides or acid chloride.
ISSN:1043-1802
1520-4812
DOI:10.1021/bc970026o