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Energy Turnover in the Normoxic and Anoxic Turtle Heart
We examined the possibility that the heart of the turtle Chrysemys scripta is an exceptional anaerobic performer, by measuring myocardial power output, lactate output, and estimated ATP turnover in perfused heart preparations. Over a range of myocardial power outputs at 5 and 15°C we find that turtl...
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Published in: | Comparative biochemistry and physiology. A, Comparative physiology Comparative physiology, 1997-05, Vol.117 (1), p.121-126 |
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container_end_page | 126 |
container_issue | 1 |
container_start_page | 121 |
container_title | Comparative biochemistry and physiology. A, Comparative physiology |
container_volume | 117 |
creator | Arthur, Peter G Franklin, Craig E Cousins, K.L Thorarensen, H Hochachka, P.W Farrell, A.P |
description | We examined the possibility that the heart of the turtle
Chrysemys scripta is an exceptional anaerobic performer, by measuring myocardial power output, lactate output, and estimated ATP turnover in perfused heart preparations. Over a range of myocardial power outputs at 5 and 15°C we find that turtle hearts perfused with anoxic saline do not show a particularly outstanding ability to produce ATP anaerobically. Furthermore, at 15°C anoxia reduced the ATP turnover rate to 50% of the normoxic rate. At 5°C the anoxia-induced depression of ATP turnover was even more pronounced, being 4-fold lower than the normoxic rate. In addition, anoxia at 5°C reduced the basal metabolic rate of the turtle heart. We conclude that long-term cardiac tolerance of hypoxia in this species is more likely related to metabolic depression rather than to an exceptional anaerobic performance. |
doi_str_mv | 10.1016/S0300-9629(96)00283-6 |
format | article |
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Chrysemys scripta is an exceptional anaerobic performer, by measuring myocardial power output, lactate output, and estimated ATP turnover in perfused heart preparations. Over a range of myocardial power outputs at 5 and 15°C we find that turtle hearts perfused with anoxic saline do not show a particularly outstanding ability to produce ATP anaerobically. Furthermore, at 15°C anoxia reduced the ATP turnover rate to 50% of the normoxic rate. At 5°C the anoxia-induced depression of ATP turnover was even more pronounced, being 4-fold lower than the normoxic rate. In addition, anoxia at 5°C reduced the basal metabolic rate of the turtle heart. We conclude that long-term cardiac tolerance of hypoxia in this species is more likely related to metabolic depression rather than to an exceptional anaerobic performance.</description><subject>Adenosine Triphosphate - metabolism</subject><subject>Anaerobic Threshold - physiology</subject><subject>Animals</subject><subject>anoxia</subject><subject>ATP</subject><subject>cardiac</subject><subject>cardiac output</subject><subject>Chrysemys scripta</subject><subject>Energy Metabolism</subject><subject>Freshwater</subject><subject>glycolysis</subject><subject>Glycolysis - physiology</subject><subject>heart rate</subject><subject>Hypoxia</subject><subject>Hypoxia - metabolism</subject><subject>lactate</subject><subject>Lactic Acid - metabolism</subject><subject>metabolic rate</subject><subject>Myocardium - metabolism</subject><subject>Oxygen Consumption</subject><subject>Physical Exertion - physiology</subject><subject>Space life sciences</subject><subject>Temperature</subject><subject>Turtles</subject><issn>0300-9629</issn><issn>1096-4940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNqFkE1PwzAMhnMAjTH4CZN6QnAoOE2aNic0ocGQJjgwzlGauhC0tiNpJ_bvyT606y62Zb_2az2EjCncU6Di4QMYQCxFIm-luANIchaLMzI8ti_Ipfc_AEAZTQdkIGmeMiaHJJs26L420aJ3TbtGF9km6r4xemtd3f5ZE-mmjCbNrgyabonRDLXrrsh5pZcerw95RD6fp4unWTx_f3l9msxjwyTr4rQwlBcJ0yK8UlUieOYCdcaSjOc0SQ3VhaTS0JJxKrJCS11VJSs0GOQCOBuRm_3dlWt_e_Sdqq03uFzqBtveq0wClyDTk0IqEp5wmQdhuhca13rvsFIrZ2vtNoqC2tJUO5pqiy0EtaOpRNgbHwz6osbyuHVAGeaP-zkGHGuLTnljsTFYWoemU2VrTzj8A8bchHU</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>Arthur, Peter G</creator><creator>Franklin, Craig E</creator><creator>Cousins, K.L</creator><creator>Thorarensen, H</creator><creator>Hochachka, P.W</creator><creator>Farrell, A.P</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope><scope>7X8</scope></search><sort><creationdate>19970501</creationdate><title>Energy Turnover in the Normoxic and Anoxic Turtle Heart</title><author>Arthur, Peter G ; Franklin, Craig E ; Cousins, K.L ; Thorarensen, H ; Hochachka, P.W ; Farrell, A.P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-5bc14b23a6030ff633986ea732748125c1ab919c1d34167ba9affd3ba0ce46043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adenosine Triphosphate - metabolism</topic><topic>Anaerobic Threshold - physiology</topic><topic>Animals</topic><topic>anoxia</topic><topic>ATP</topic><topic>cardiac</topic><topic>cardiac output</topic><topic>Chrysemys scripta</topic><topic>Energy Metabolism</topic><topic>Freshwater</topic><topic>glycolysis</topic><topic>Glycolysis - physiology</topic><topic>heart rate</topic><topic>Hypoxia</topic><topic>Hypoxia - metabolism</topic><topic>lactate</topic><topic>Lactic Acid - metabolism</topic><topic>metabolic rate</topic><topic>Myocardium - metabolism</topic><topic>Oxygen Consumption</topic><topic>Physical Exertion - physiology</topic><topic>Space life sciences</topic><topic>Temperature</topic><topic>Turtles</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arthur, Peter G</creatorcontrib><creatorcontrib>Franklin, Craig E</creatorcontrib><creatorcontrib>Cousins, K.L</creatorcontrib><creatorcontrib>Thorarensen, H</creatorcontrib><creatorcontrib>Hochachka, P.W</creatorcontrib><creatorcontrib>Farrell, A.P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>MEDLINE - Academic</collection><jtitle>Comparative biochemistry and physiology. A, Comparative physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arthur, Peter G</au><au>Franklin, Craig E</au><au>Cousins, K.L</au><au>Thorarensen, H</au><au>Hochachka, P.W</au><au>Farrell, A.P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Energy Turnover in the Normoxic and Anoxic Turtle Heart</atitle><jtitle>Comparative biochemistry and physiology. A, Comparative physiology</jtitle><addtitle>Comp Biochem Physiol A Physiol</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>117</volume><issue>1</issue><spage>121</spage><epage>126</epage><pages>121-126</pages><issn>0300-9629</issn><issn>1096-4940</issn><abstract>We examined the possibility that the heart of the turtle
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source | ScienceDirect Journals |
subjects | Adenosine Triphosphate - metabolism Anaerobic Threshold - physiology Animals anoxia ATP cardiac cardiac output Chrysemys scripta Energy Metabolism Freshwater glycolysis Glycolysis - physiology heart rate Hypoxia Hypoxia - metabolism lactate Lactic Acid - metabolism metabolic rate Myocardium - metabolism Oxygen Consumption Physical Exertion - physiology Space life sciences Temperature Turtles |
title | Energy Turnover in the Normoxic and Anoxic Turtle Heart |
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