Number of correlates of membrane metabolism and long-term potentiation in rat brain slices

Long-term potentiation was elicited in living slices of rat olfactory cortex by stimulation of the lateral olfactory tract. A group of interdependent parameters of membrane metabolism was studied, i.e., the kinetics of 45Ca metabolism, lipid peroxidation, and antioxidant defense; cytochemical measur...

Full description

Saved in:
Bibliographic Details
Published in:Neuroscience and behavioral physiology 1997-05, Vol.27 (3), p.221-224
Main Authors: Emel'yanov, N A, Glushchenko, T S, Izvarina, N L, Malikov, U M, Nilova, N S, Sokolova, N E, Tokarev, A V
Format: Article
Language:English
Subjects:
Acetylcholine - metabolism
Animals
Antioxidants
Antioxidants - metabolism
Brain - enzymology
Brain Chemistry - physiology
Brain slice preparation
Calcium - metabolism
Cortex (olfactory)
Electric Stimulation
Glial cells
GTP Phosphohydrolases - metabolism
In Vitro Techniques
Kinetics
Lipid metabolism
Lipid peroxidation
Lipid Peroxidation - physiology
Long-term potentiation
Long-Term Potentiation - physiology
Membranes - metabolism
Metabolism
Na+/K+-exchanging ATPase
Neuroglia - metabolism
Neuronal-glial interactions
Neurons - metabolism
Rats
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Long-term potentiation was elicited in living slices of rat olfactory cortex by stimulation of the lateral olfactory tract. A group of interdependent parameters of membrane metabolism was studied, i.e., the kinetics of 45Ca metabolism, lipid peroxidation, and antioxidant defense; cytochemical measurements were made of Na+, K(+)-ATPase activity in neurons and glial cells; the functional (GTPase) activity of G-proteins was also studied. All parameters were compared with the bioelectrical activity of slices at three time points after tetanization, i.e., 3-5, 15, and 30 min. In most cases, regular phasic changes in metabolic parameters occurred, and their functional significance is discussed.
ISSN:0097-0549
1573-899X
DOI:10.1007/BF02462882