Cardiovascular involvement in relapsing polychondritis

Relapsing polychondritis is an inflammatory disease that characteristically involves cartilagenous tissues. Cardiovascular involvement is a fairly common complication and the second most frequent cause of mortality in this disease. The case of a man with a progressive cardiac involvement, aortic inc...

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Bibliographic Details
Published in:Seminars in arthritis and rheumatism 1997-06, Vol.26 (6), p.840-844
Main Authors: Del Rosso, Attilio, Petix, Nunzia Rosa, Pratesi, Mauro, Bini, Alessandro
Format: Article
Language:English
Subjects:
Aged
Aortic Aneurysm - complications
Aortic Aneurysm - pathology
Aortic Valve Insufficiency - complications
Aortic Valve Insufficiency - pathology
Biological and medical sciences
Cardiovascular Diseases - complications
Cardiovascular Diseases - pathology
Heart Block - complications
Heart Block - pathology
Humans
Male
Medical sciences
Mitral Valve Insufficiency - complications
Mitral Valve Insufficiency - pathology
Polychondritis, Relapsing - complications
Polychondritis, Relapsing - pathology
Polychondritis, Relapsing - therapy
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
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Summary:Relapsing polychondritis is an inflammatory disease that characteristically involves cartilagenous tissues. Cardiovascular involvement is a fairly common complication and the second most frequent cause of mortality in this disease. The case of a man with a progressive cardiac involvement, aortic incompetence, mitral regurgitation, and finally complete atrioventricular block offered the opportunity of reviewing the cardiovascular complications in relapsing polychondritis. The most frequent abnormalities are aortic regurgitation and aortic aneurysm. Furthermore, several cases of atrioventricular block, mitral regurgitation, and acute pericarditis have been reported. For early diagnosis and treatment of these severe complications, periodic cardiovascular examination is mandatory in these patients.
ISSN:0049-0172
1532-866X
DOI:10.1016/S0049-0172(97)80028-5