Study of the immunostimulating effect of glycophosphopeptical (AM3) in mice

The results of this study show that glycophosphopeptical (AM-3) has a marked immunostimulant effect in mice, in terms of an increase in the number of haemolytic plaque-forming B lymphocytes producing antibodies against sheep erythrocytes as compared with saline-treated controls. The results also dem...

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Bibliographic Details
Published in:FEMS immunology and medical microbiology 1997-05, Vol.18 (1), p.87-89
Main Authors: Gallego Olivella, J, Fadurdo Torrus, E
Format: Article
Language:English
Subjects:
Adjuvants, Immunologic
AM3
Animals
B-Lymphocytes - immunology
Biological and medical sciences
Calcium Phosphates - administration & dosage
Calcium Phosphates - immunology
Glycopeptides - administration & dosage
Glycopeptides - immunology
Glycophosphopeptical
Guinea Pigs
Hemolytic Plaque Technique
Immunologic Factors - administration & dosage
Immunologic Factors - immunology
Immunomodulators
Immunopotentiator
Immunostimulant
Medical sciences
Mice
Pharmacology. Drug treatments
Plaque-forming assay
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Summary:The results of this study show that glycophosphopeptical (AM-3) has a marked immunostimulant effect in mice, in terms of an increase in the number of haemolytic plaque-forming B lymphocytes producing antibodies against sheep erythrocytes as compared with saline-treated controls. The results also demonstrate the activity of this drug when administered intraperitoneally.
ISSN:0928-8244
1574-695X
DOI:10.1016/S0928-8244(97)00018-7